Pharmaceutical composition, use of a protoporphyrin precursor photochemotherapeutic agent together with a photosensitizer for localization of vascular stroma, product containing the same, kit for use in photochemotherapy of disorders or abnormalities of the external or internal surfaces of the body, and photochemical chemotherapy treatment processes for disorders or abnormalities of external or internal surfaces of the body, and in vitro diagnosis of abnormalities or disorders, by testing a sample of body fluids or tissues from a patient

摘要

"PHARMACEUTICAL COMPOSITION, USE OF A PROTOPORPHIRINE PRECURSOR PHOTOQUIMIOTHERAPEUTIC AGENT WITH A PHOTOSENSITIZER OF VASCULAR STROMA, PRODUCT CONTAINING THE SAME, KIT FOR USE IN PHOTOQUIMIOTHERAPY OF DISTURSES OF OTHEROMY THERAPEUTIC THERAPEUTIC THERAPY OF THERAPEUTIC DETERMINISTS. DISORDERS OR ABNORMALITIES OF EXTERNAL OR INTERNAL BODY SURFACES, AND IN VITRO DIAGNOSIS OF ABNORMALITIES OR DISORDERS, BY TESTING A BODY FLUID SAMPLE OR TISSUE FROM A PATIENT ". The invention provides pharmaceutical compositions comprising a protoporphyrin precursor photochemotherapeutic agent, together with photosensitizers for vascular stroma localization, optionally together with at least one auxiliary agent for superficial penetration and, optionally, with one or more chelating agents, and its use in treatment of disorders or abnormalities that are responsive to PDT, preferably presenting synergistically enhanced therapy, kits comprising them and processes of therapy and diagnosis.