Compounds and processes for the treatment of bacterial dysentery using antibiotics and toxin-binding oligosaccharide compositions

摘要

Invention Patent: B "COMPOUNDS AND PROCESSES FOR THE TREATMENT OF BACTERIAL DININTERIA USING TOXIN-BINDING ANTIBIOTICS AND OLIGOSACARIDAL COMPOSITIONS" D This invention relates to the treatment of diarrhea and related conditions caused by infection by E. coli pathogenic. More specifically, this invention is directed to the unexpected discovery that by administering a composition that binds and removes the shiga-like toxins (SLT) produced by pathogenic E. coli whenever an antibiotic is administered, improved treatment is provided. New compositions are provided that contain both the antibiotic and the toxin-binding composition and processes for treatment that use simultaneous administration of the toxin-binding composition whenever the antibiotic is administered. These compositions and processes kill the E. coli enteric organisms that produce the conditions and neutralize the SLT produced by the organisms and / or released from the organisms when they are killed. Thus, these conditions and processes are better able to improve the symptoms of the infection and to inhibit the progression of this infection to hemolytic uremic syndrome (HUS) than conventional treatment.