Compounds 4 - Carboxy - methyl - 2 - amino - 1,2,3,4 - Tetrahidroquinolina Pharmacist, Pharmaceutical Composition and kit comprising Said CompoundAnd their use as inhibitors of the Colesteril ester transfer protein (CETP) in the treatment of Peripheral Vascular Disease, atherosclerosis, dyslipidemia, hipergliceridemia.

摘要

Inhibitors of the ester transfer protein in colesterilico consitentes carboxiamono - 2 - 4 - methyl - 1,2,3,4 - tetrahidroquinolinas formula I,Pharmaceutical compositions containing including "kits" and the use of these inhibitors to raise certain lipid levels in plasma.Including high density lipoprotein cholesterol and other lipid levels to decrease in plasma such as LDL cholesterol and triglycerides.And therefore to treat diseases that are exacerbated by low levels of HDL cholesterol and / or high levels of LDL cholesterol and triglycerides.Cardiovascular Diseases such as atherosclerosis and in some Mammals, including human beings.