Matrix metalloproteinase inhibitors of matrix metalloproteinase Enzymes of butyric acid and Treatment method using the same

摘要

A compound characterized by the idonde equation: R7X is O, nor9,S, OH, SH or NN R7a R7 and R7a independently are Hydrogen, alkyl, C1-C20 or substituted alkyl C1-C20 '(CH2) 0-6 -aryl, (CH2) 0-6 -Heteroaryl, or (CH2) 0 -6-Cycloalkyl; R1 and R2 independently are Hydrogen, C1-C20 alkyl or C1-C20'alkyl substituted, NO2, CN, CHO, COR6, COOR6, SO3 R6, OR6, CONR and R6, (CH2) o-6 -Aryl, (CH2) o-6-heteroaryl, or (CH2) o-6-Cycloalkyl; R6 is hydrogen, C1-C20 alkyl substituted C1-C20 alkyl, Aryl is phenyl or substituted phenyl, R3 is hydroxy, O-C1-C20 alkyl or O-C1-C20 substituted alkyl, O- (CH) 1-3 aryl or NHOR6;R4 and R5 are independent hydrogen, C1-C20 tar or C1-C20 alternative tar, c2-c20 alquenio or c2-c20 alquenilo alternative (CH2) 0-6 arilo (CH2) 0-6 - (or s) - arilo (CH2) 0-6 - (or s) - foreign matters; or R4,R5...This is hydrogen. The other is: cor8 csr8 conr8 R9, CSN8 R9, coor8, cosr8