Diagnostic agent comprising an amino acid or peptide containing at least one 13C or 14C for pancreatic exocrine function

摘要

A diagnostic agent for testing pancreatic exocrine function. The agent comprises an amino acid or a peptide containing at least one 13C or 14C atom with the proviso that the pharmaceutical salt is not Bz-Tyr-13C-PABA. The amino acid is represented by the following formula (I): X1-R1-Y1 Wherein X1 is a hydrogen atom or a protecting group, R1 is a peptide of 2 to 50 amino acids an amino acid or a single bond, Y1 is an amino acid optionally having a protecting group. The diagnostic agent, upon reaction with pancreatic exocrine protease is decarboxylated to generate 13CO2 or 14CO2 and may be used in a breath test.