Combination of metastatic farnesilo inhibitors and antineoplastic agents and / or radiation therapy in the treatment of diffuse diseases

摘要

It refers to the use of (a) a preparation for inhibiting Falun phenyltransferase (FPT), such as fusion cyclobenzocyclohexane, oligarchic cucumber, Mimosa cucumber, Mimosa cucumber or farnesilado derivative; (b) an anti-tumor agent, which affects microtubules such as uracilo mustard, closetina, cyclophosphamide, ifosfamida, etc, In this paper, the author analyzes the characteristics of,Vinclistina, gemcitabina, paclitaxel, tabotere et al. When the inhibitor of PFT formula A, X 'is h, halogen; y' is h, coor ';R's C1-C12, phenyl, lease, 2-piseriallo, etc.; the chemotherapy agent is not anthrax base, epipodofilloxinas, anthrax antibiotic, D, etc.; the chemotherapy agent can be used to treat lung cancer, pancreatic cancer, colon cancer and other diffuse diseases. Myeloid leukemia, melanoma, thyroid cancer, vesicular cancer, blood cell cancer, poliomyelitis, breast cancer, prostate cancer