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DERIVATIVES OF NITROMETHYLTHIOBENZENE AS INHIBITORS OF ALDOSIC REDUCTASE
DERIVATIVES OF NITROMETHYLTHIOBENZENE AS INHIBITORS OF ALDOSIC REDUCTASE
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机译:亚氨基甲基硫代苯衍生物对醛糖还原酶的抑制作用
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摘要
The invention concerns novel compounds of general formula (1), their tautomeric forms, and their additive salts with pharmaceutically acceptable bases. The invention also concerns methods for preparing these compounds and their applications as medicines. These compounds inhibit the aldose reductase enzyme and can be used in the treatment or prevention of peripheral and autonomous neurological diabetic complications, renal and ocular disorders such as cataract and retinopathy.
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