首页> 外文学位 >Development of potent and selective inhibitors of Mycobacterium tuberculosis, Plasmodium falciparum and Staphylococcus aureus dihydrofolate reductase

【24h】

Development of potent and selective inhibitors of Mycobacterium tuberculosis, Plasmodium falciparum and Staphylococcus aureus dihydrofolate reductase

机译：结核分枝杆菌，恶性疟原虫和金黄色葡萄球菌二氢叶酸还原酶的有效和选择性抑制剂的开发

获取原文

获取原文并翻译 | 示例

页面导航

著录项
相似文献
相关主题

著录项

作者
Jung, Hunmin;
展开▼
作者单位

Texas A&M University;

展开▼
授予单位 Texas A&M University;
学科
学位 Ph.D.
年度 2014
页码 197 p.
总页数 197
原文格式 PDF
正文语种 eng
中图分类
关键词

相似文献

外文文献
中文文献
专利

1. 1,3,5-triazaspiro[5.5]undeca-2,4-dienes as selective Mycobacterium tuberculosis dihydrofolate reductase inhibitors with potent whole cell activity [J] . Xuan Yang, Wassihun Wedajo, Yoshiyuki Yamada, European Journal of Medicinal Chemistry: Chimie Therapeutique . 2018,第期

机译：1,3,5-三咔啉[5.5] UNDECA-2,4-DIENES作为选择性分枝杆菌二氢化酸盐酸还原酶抑制剂，具有有效的全细胞活性
2. In silico structure-based design of a novel class of potent and selective small peptide inhibitor of Mycobacterium tuberculosis Dihydrofolate reductase, a potential target for anti-TB drug discovery [J] . Kumar M., Vijayakrishnan R., Subba Rao G. Molecular diversity . 2010,第3期

机译：基于计算机模拟的结核分枝杆菌二氢叶酸还原酶的新型有效和选择性小肽抑制剂类别的设计，这是抗结核药物发现的潜在目标
3. Structural comparison of chromosomal and exogenous dihydrofolate reductase from Staphylococcus aureus in complex with the potent inhibitor trimethoprim. [J] . Heaslet H, Harris M, Fahnoe K Proteins: Structure, Function, and Genetics . 2009,第3期

机译：金黄色葡萄球菌的染色体和外源性二氢叶酸还原酶与有效抑制剂甲氧苄啶复合的结构比较。
4. Identification of Plasmodium falciparum thioredoxin reductase (PfTrxR) inhibitors from Malaria Box using LC-MS functional assay [C] . Angela I. Calderon, Neil Tiwari, Katja Becker ASMS Conference on Mass Spectrometry and Allied Topics . 2014

机译：使用LC-MS功能测定法鉴定来自疟疾盒的疟原虫氧化嗪（PFTRXR）抑制剂
5. Characterization of folate cycle enzymes in Plasmodium falciparum: Ligand binding properties of dihydrofolate reductase, thymidylate synthase, and serine hydroxymethyltransferase. [D] . Pang, Cullen Kwai Tim. 2008

机译：恶性疟原虫中叶酸循环酶的特征：二氢叶酸还原酶，胸苷酸合酶和丝氨酸羟甲基转移酶的配体结合特性。
6. Structure-Based Approach to the Development of Potent and Selective Inhibitors of Dihydrofolate Reductase from Cryptosporidium [O] . David B. Bolstad, Erin S. D. Bolstad, Kathleen M. Frey, -1

机译：基于结构的方法开发隐孢子虫二氢叶酸还原酶的有效和选择性抑制剂
7. Development of Selective Inhibitors of Dihydrofolate Reductase (DHFR) of Mycobacterium Tuberculosis [O] . Alfaraj Rihaf 2013

机译：结核分枝杆菌二氢叶酸还原酶（DHFR）选择性抑制剂的开发。

Development of potent and selective inhibitors of Mycobacterium tuberculosis, Plasmodium falciparum and Staphylococcus aureus dihydrofolate reductase

著录项

相似文献

相关主题

期刊订阅