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Compounds for Immunotherapy of Prostate Cancer.
Compounds for Immunotherapy of Prostate Cancer.
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机译:用于前列腺癌免疫治疗的化合物。
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摘要
A polypeptide composed of the immune part or variant of prostate protein, wherein the protein comprises a series of amino acids, encoded by DNA molecules, and a selected chain in the nucleoside chain group listed in SEQ No. 2, 3 and 8, 29, 41-45, 47, 52, 54-65, 7 o, 73-74, 79, 81, 87, 90, 92, 93, 97, 103, 104, 107, 109-111, 115-160, 171, 173, 175 and 177,The appendages of these nuclear chains and variants of the same chain. The DNA molecule consists of a nucleoside chain that encodes the polypeptide in requirement 1. 1. Pharmacological compounds for the treatment of prostate cancer, including a polypeptide and a carrier without physiological rejection, in which the polypeptide includes the immune part of prostate protein or its variants,The protein consists of an amino acid chain encoded by a DNA molecule, which is supplemented by a selected chain in the nuclear chain set of SEQ No. 5-7, 30, 40, 46, 53, 66-69, 71, 72, 75, 78, 80, 82-86, 88, 89, 91, 94-96, 98-102, 105, 106 and 161-170. Nuclear chain and variants of the same chain. 1. Vaccines for prostate cancer, including a peptide and a non-specific immune response enhancer, in which the peptide includes the immune part or variant of prostate protein,The protein consists of an amino acid chain encoded by a DNA molecule with a selected chain in the nuclear chain set of SEQ No. 5-7, 30, 40, 46, 53, 66-69, 71, 72, 75, 78, 80, 82-86, 88, 89, 91, 94-96, 98-102, 105, 106 and 161-170, The appendages of these nuclear chains and variants of the same chain.
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机译:由前列腺蛋白的免疫部分或变体组成的多肽,其中该蛋白包含由DNA分子编码的一系列氨基酸,以及SEQ ID NO:2、3和8、29中所列的核苷链基中的选定链, 41-45、47、52、54-65、7o,73-74、79、81、87、90、92、93、97、103、104、107、109-111、115-160、171、173 175和177,这些核链的附属物和同一链的变体。 DNA分子由编码要求1中的多肽的核苷链组成。1.用于治疗前列腺癌的药理化合物,包括多肽和无生理排斥的载体,其中多肽包括前列腺蛋白或其免疫部分该蛋白质由DNA分子编码的氨基酸链组成,并由SEQ ID No. 5-7、30、40、46、53、66-69、71, 72、75、78、80、82-86、88、89、91、94-96、98-102、105、106和161-170。核链和同一链的变体。 1.前列腺癌疫苗,包括一种肽和一种非特异性免疫应答增强剂,其中的肽包括前列腺蛋白的免疫部分或变体。该蛋白由DNA分子编码的氨基酸链组成,具有选定的链在SEQ ID No.5-7、30、40、46、53、66-69、71、72、75、78、80、82-86、88、89、91、94-96、98的核链组中-102、105、106和161-170,这些核链的附件和同一链的变体。
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