process for spraying and electrostatic charging of the powder intended for administration mainly by inhalation and device for feeding.spraying and electrostatic charging of the powder intended for administration mainly by inhalation

摘要

The invention discloses a method and a device for de-agglomeration and electrostatic charging of a fine powder preferably intended for inhalation purposes. The electrostatic charging takes place by means of tribo, corona and/or inductive charging. The device according to the invention is particularly intended for being able to dose decomposed powder directly into the inspiration air for administering of, for instance, active pharmaceutical substances, alternatively provide a further dosing device with electrostatically charged de-agglomerated powder for an even more controlled dosing of the substance into the inspiration air. De-agglomeration preferably takes place in that two rotating brushes containing powder are touching each other. The bristles are rubbed against each other and thereby decompose the powder agglomerates. The rotation speed of the brushes is suitably optimized to achieve the best possible result for different powder substances. The design of the brushes is further optimized for the substances, which are to be de-agglomerated and electrostatically charged prior to an administering step.