method and apparatus for detecting and reporting conditions of derailment in a railway vehicle.

• 1. 一种铁路车辆脱轨检测装置及其使用方法 [P] . 中国专利： CN112498417A . 2021-03-16
• 2. 脱轨检测装置以及相关的铁路车辆和方法 [P] . 中国专利： CN110893867A . 2020-03-20
• 3. method and apparatus for detecting and reporting conditions of derailment in a railway vehicle. [P] . ITTO20000551A1 . 2001-12-10

  机译： 检测和报告铁路车辆脱轨情况的方法和设备。

• 4. Method and apparatus for detecting and signalling derailment conditions in a railway vehicle [P] . 美国专利： US6860453B2 . 2005-03-01

  机译： 用于检测和发出铁路车辆脱轨状况的方法和装置

• 5. METHOD AND APPARATUS FOR DETECTING AND SIGNALLING DERAILMENT CONDITIONS IN A RAILWAY VEHICLE [P] . 欧洲知识产权局专利： EP1292482A1 . 2003-03-19

  机译： 用于检测和通知铁路车辆中的破损状况的方法和装置

• 1. Derailment risk and dynamics of railway vehicles in curved tracks: Analysis of the effect of failed fasteners [J] . Silvia Morales-Ivorra, Julia Irene Real, César Hernández, 现代交通学报（英文版） . 2016,第001期
• 2. Derailment risk and dynamics of railway vehicles in curved tracks： Analysis of the effect of failed fasteners [J] . Silvia, Morales-Ivorra, Julia, 现代交通学报：英文版 . 2016,第001期
• 3. Research on Pantograph and Overhead Contact System's Simulation of High Speed Railway and Comparison of Three Calculation Methods by Finite Element Method [J] . PANG Zhining, LIU Yin, WANG Dongming, 国际设备工程与管理（英文版） . 2021,第001期
• 4. Railway Vehicle Derailment Simulation for Derailment Detection System in Early Signs [C] . Masahiko Aki, Chiehjen Hung, Takayoshi Yamashita, Asian conference on multibody dynamics;ACMD 2010 . 2011
• 5. A survey of United States railway safety based on accident data reported to the Federal Railway Administration over a ten year period with a comparative analysis to a Federal Aviation Administration airplane design safety target. [D] . Pickett, Stephen James. 2001
• 6. NOx NH3 N2O and PN real driving emissions from a Euro VI heavy-duty vehicle. Impact of regulatory on-road test conditions on emissions [O] . Pablo Mendoza-Villafuerte, Ricardo Suarez-Bertoa, Barouch Giechaskiel, -1
• 7. Application of Oil-Hydraulic Actuator for Active Suspension of Railway Vehicle. Investigation with Optimal Regulator Using a Scale Model on a Test Apparatus. [O] . Katsuya Tanifuji, Ryo-Hei Shimamune, Hiroaki Nagura 1994

• 1. BACKGROUND： Vibrio vulnifi cus inside the body could activate the NF-!B signaling pathwayand initiate the inflammatory cascade. The lung is one of the earliest organs affected by sepsisassociated with acute lung injury. High mobility group protein B1 （HMGB1） is an important late-actingpro-infl ammatory cytokine involving in the pathophysiology of sepsis. It is also involved in the injuryprocess in the lung, liver and intestine. There has been no report on the involvement of HMGB1 inVibrio vulnifi cus sepsis-induced lung injury.METHODS： Sixty rats were randomly divided into a normal control group （group A, n=10） anda Vibrio vulnificus sepsis group （group B, n=50）. Sepsis was induced in the rats by subcutaneousinjection of Vibrio vulnificus （concentration 6×108 cfu/mL, volume 0.1 mL/100g）） into the left lowerlimbs. The rats in group B were sacrifi ced separately 1, 6, 12, 24, and 48 hours after the infection.Their lungs were stored as specimens, lung water content was measured, and lung pathology wasobserved under a light microscope. The expressions of the HMGB1 gene and protein in the lungswere detected by RT-PCR and Western blot. Data were analyzed with one-way analysis of variance（ANOVA） and the LSD method for pair-wise comparison between the two groups. P〈0.05 wasconsidered statistically signifi cant.RESULTS： Compared to group A （0.652±0.177）, HMGB1 mRNA expression in the lungs ofgroup B was signifi cantly higher at 0 hour （1.161±0.358, P=0.013）, 24 hours （1.679±0.235, P=0.000）,and 48 hours （1.258±0.274, P=0.004） （P〈0.05）, and peaked at 24 hours. Compared to group A（0.594±0.190）, HMGB1 protein expression at 6 hours （1.408±0.567, P=0.026） after infection wassignificantly increased （P〈0. 05）, and peaked at 24 hours （2.415±1.064, P=0.000） after infection.Compared to group A （0.699±0.054）, lung water content was significantly increased at 6 hours（0.759±0.030, P=0.001）,12 hours （0.767±0.023, P=0.000）, 24 hours （0.771±0.043, P=0.000） and 48hours （0.789±0.137, P=0.000） after infection （P〈0.05）. Compared to group A, pathological changesat 12 hours in group B indicate marked pulmonary vascular congestion, interstitial edema andinfl ammatory infi ltration. Alveolar cavity collapse and boundaries of the alveolar septum could not beclearly identifi ed.CONCLUSION： Vibrio vulnifi cus sepsis can lead to injury in rat lungs, and increased HMGB1expression in lung tissue may be one of the mechanisms for injury from Vibrio vulnifi cus sepsis. [J] . Qiao-meng Qiu ,Zhong-wang Li ,Lu-ming Tang . 世界急诊医学杂志(英文) . 2011,第4期
• 2. A Secure Routing Method for Detecting False Reports and Wormhole Attacks in Wireless Sensor Networks [J] . Hyeon Myeong Choi ,Su Man Nam ,Tae Ho Cho . 无线传感网络（英文） . 2013,第3期
• 3. 铁路车辆脱轨检测装置 [C] . . 2007年中国铁道学会年会 . 2007
• 4. 考虑多源检测设备分布情况的高速公路路段拥堵检测 [A] . 冯寻 . 2019