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EXPANDABLE GASTRORETENTIVE THERAPY SYSTEM HAVING A PROLONGED GASTRIC RESIDENCE TIME

机译:具有较长胃驻留时间的可扩展胃张力治疗系统

摘要

The invention relates to a device for delaying the pylorus passage of orally administered medicament forms. Said device comprises a component which expan ds upon contact with the gastric juice and a polymer coat which is permeable to liquids but not to gases. The device can contain an active substance whose release into the gastric juice is mainly controlled by the medicament form into which it is incorporated. Unlike conventional medicament forms with delayed pylorus passage, the release of the active substance does not so muc h depend on the kind and structure of the polymer coat but is mainly determine d by the incorporated medicament form. The inventive device can be easily roll ed or folded and can be filled into capsules.
机译:本发明涉及一种用于延迟口服给药的药物形式的幽门通过的装置。所述装置包括在与胃液接触时膨胀的组分和对液体可渗透但对气体不可渗透的聚合物涂层。该装置可以包含活性物质,其向胃液中的释放主要由掺入其中的药物形式控制。与幽门途径延迟的常规药物形式不同,活性物质的释放并不取决于聚合物包衣的类型和结构,而是主要取决于所掺入的药物形式。本发明的装置可以容易地滚动或折叠并且可以填充到胶囊中。

著录项

  • 公开/公告号CA2344672A1

    专利类型

  • 公开/公告日2000-05-11

    原文格式PDF

  • 申请/专利权人 LTS LOHMANN THERAPIE-SYSTEME AG;

    申请/专利号CA19992344672

  • 发明设计人 KRUMME MARKUS;

    申请日1999-10-23

  • 分类号A61K9/00;

  • 国家 CA

  • 入库时间 2022-08-22 01:52:39

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