USE OF AN IMMUNO COMPLEX FOR THE PREPARATION OF A THERAPEUTIC COMPOSITION USEFUL FOR TRANSFECTING A POLYNUCLEOTIDE INTO MACROPINOCYTE CELLS

摘要

Described is the use of an immuno complex, which comprises at least oneantibody or a reactive part thereof and at least one polynucleotide, for thepreparation of a therapeutic composition for the introduction of apolynucleotide into a macropinocyte target cell wherein said immuno complexhas a particle size selected between 0.5 µm and 6 µm.