首页> 外国专利> Use of an enterobacterium protein ompa associated with an antigen for generatingan antiviral, antiparasitic or antitumoral cytotoxic response

Use of an enterobacterium protein ompa associated with an antigen for generatingan antiviral, antiparasitic or antitumoral cytotoxic response

机译:与抗原相关的肠杆菌蛋白ompa在产生抗病毒,抗寄生虫或抗肿瘤细胞毒性反应中的用途

摘要

The invention concerns the use of an enterobacterium membrane protein OmpA, in particular of Klebsiella pneumoniae, associated with an antigen or a hapten for preparing a pharmaceutical composition designed to generate or enhance a cytotoxic T response directed against a tumor cell. The invention also concerns the use of said compounds for preventing or treating infection or cancer, in particular cancers associated with a tumoral antigen such as melanoma, and pharmaceutical compositions comprising some of said compounds.
机译:本发明涉及与抗原或半抗原相关的肠细菌膜蛋白OmpA,特别是肺炎克雷伯氏菌,在制备用于产生或增强针对肿瘤细胞的细胞毒性T应答的药物组合物中的用途。本发明还涉及所述化合物用于预防或治疗感染或癌症,特别是与诸如黑色素瘤之类的肿瘤抗原相关的癌症的用途,以及包含某些所述化合物的药物组合物。

著录项

  • 公开/公告号AU2809300A

    专利类型

  • 公开/公告日2000-09-04

    原文格式PDF

  • 申请/专利权人 PIERRE FABRE MEDICAMENT;

    申请/专利号AU2809300A

  • 发明设计人 TOUFIC RENNO;JEAN-YVES BONNEFOY;

    申请日2000-02-17

  • 分类号A61K39/00;A61K48/00;A61P31/00;A61P33/00;A61P35/00;A61K39/385;C07K14/26;C12N15/62;

  • 国家 AU

  • 入库时间 2022-08-22 01:52:06

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