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SIMULTANEOUS DRUG TESTING AND FINGERPRINTING ASSAY

机译:同时进行药物测试和指纹鉴定

摘要

A method and device for testing for the presence of substances such as drugs in body fluids while simultaneously positively identifying the test subject. The device comprises an absorbent pad and a membrane mounted to the absorbent pad containing a plurality of separated areas provided with different immobilized ligand having a specific receptor site for capture or rejection of specific antigens produced by different predetermined drugs. The method of testing comprises the steps of: (a) obtaining a quantity of body fluid in a container, (b) adding an antibody to the body fluid to form a mixed solution, (c) placing the mixed solution on a membrane and absorbent pad device and immobilized ligands, (d) covering the finger with a thin film of labelled antibody and (e) placing the finger on the membrane containing immobilized ligand specifically selected to bind to labelled antibody presenting the fingerprint of the test subject, the presence or absense of substances being tested for in the body fluid so that solution is deposited from the finger on the membrane indicating presence or absence of the substance.
机译:一种用于测试体液中是否存在诸如药物之类的物质的方法和设备,同时可以肯定地识别出测试对象。该装置包括吸收垫和安装到该吸收垫上的膜,该膜包含多个分离的区域,该分离的区域设有不同的固定的配体,该固定的配体具有用于捕获或排斥由不同的预定药物产生的特定抗原的特定受体位点。测试方法包括以下步骤:(a)在容器中获得一定量的体液;(b)向体液中添加抗体以形成混合溶液;(c)将混合溶液置于膜和吸收剂上垫装置和固定的配体,(d)用标记的抗体薄膜覆盖手指,以及(e)将手指放在含有固定的配体的膜上,固定的配体经过特别选择以与标记的抗体结合,从而呈现测试对象的指纹,体液中缺少要测试的物质,因此溶液从手指上沉积在膜上,表明该物质存在或不存在。

著录项

  • 公开/公告号EP0643834B1

    专利类型

  • 公开/公告日2000-08-16

    原文格式PDF

  • 申请/专利权人 MINA LTD;

    申请/专利号EP19920920466

  • 发明设计人 GUIRGUIS RAOUF A.;

    申请日1992-09-14

  • 分类号G01N33/543;G01N33/553;G01N33/94;A61B5/117;

  • 国家 EP

  • 入库时间 2022-08-22 01:49:11

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