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METHOD AND DEVICE FOR PROVIDING NICOTINE REPLACEMENT THERAPY TRANSDERMALLY/TRANSBUCCALLY
METHOD AND DEVICE FOR PROVIDING NICOTINE REPLACEMENT THERAPY TRANSDERMALLY/TRANSBUCCALLY
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机译:经皮/经皮提供烟碱替代疗法的方法和装置
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摘要
A skin or buccal patch for providing nicotine replacement therapy which comprises a matrix type laminated composite in which the matrix is composed of a mixture of nicotine in a polymer (12) wherein the amount of nicotine in the matrix, diffusion coefficient of nicotine in the matrix and the thickness of matrix are such that the release of nicotine is: (1) controlled by the patch; (2) rapid and at a relatively high flux over the prescribed wearing time of patch; and (3) such that a substantial proportion of the nicotine initially in the patch has been released at the end of the prescribed wearing time. The laminated composite also comprises an impermeable backing layer (11) and a removable release liner (13).
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