首页> 外国专利> A therapeutic agent for pathology caused by increased expression of genes dependent on the transcription factor ETS1 or ETS2

A therapeutic agent for pathology caused by increased expression of genes dependent on the transcription factor ETS1 or ETS2

机译:由依赖转录因子ETS1或ETS2的基因表达增加引起的病理学治疗剂

摘要

The present invention inhibits the transcriptional function of transcription factor ets1 or ets2 by CDK inhibitors, thereby causing pathological phenomena caused by increased expression of genes dependent on transcription factor ets1 or ets2, such as rheumatoid and cancer cell metastases. In relation to the present invention, therapeutic agents for pathologies caused by increased expression of genes dependent on the transcription factor ets1 or ets2 of the present invention include CDK inhibitors such as Flavopyridol and Olomucin.
机译:本发明通过CDK抑制剂抑制转录因子ets1或ets2的转录功能,从而引起由依赖于转录因子ets1或ets2的基因的表达增加引起的病理现象,例如类风湿和癌细胞转移。关于本发明,由依赖于本发明的转录因子ets1或ets2的基因表达增加引起的病理学治疗剂包括CDK抑制剂,例如黄酮吡啶醇和Olomucin。

著录项

  • 公开/公告号KR19990085357A

    专利类型

  • 公开/公告日1999-12-06

    原文格式PDF

  • 申请/专利权人 성재갑;

    申请/专利号KR19980017731

  • 发明设计人 양범석;김동명;

    申请日1998-05-16

  • 分类号A61K31/35;A61K31/425;

  • 国家 KR

  • 入库时间 2022-08-22 01:46:28

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