- PROCESS FOR THE PREPARATION OF ORTHO-SUBSTITUTED ARYLMETAL COMPOUNDS AND THEIR REACTION WITH ELECTROPHILIC REAGENTS

摘要

The present invention is alkyl in the presence of a secondary metal amide of a catalytic amount of - or an aryl with the metal compound or a metal hydride, characterized by Sikkim deprotonation of an aromatic compound, with at least one halogen atom, a trifluoromethoxy group, a dialkylamino a method of preparing a substituted aryl metal compound, and reacting this compound with an electrophilic reagent-groups, by nitrile groups, alkoxy groups or dialkyl amido ride the aromatic compound having a hydrogen atom at the ortho-position to the group protonated ortho relate to.