MUCOADHESIVE POLYMER COMPLEX AND ITS APPLICATION IN PHARMACEUTICAL FIELD

摘要

The present invention relates to polyethylene glycol, polypropylene glycol, polyethylene glycol macromer, polypropylene glycol macromer, polyethylene glycol / polypropylene glycol copolymer, or polyethylene glycol / polypropylene glycol copolymer macromer and alkoxy derivatives thereof, polyethylene oxide / The present invention relates to a new mucoadhesive polymer composite obtained by polymerizing acrylic acid using a polypropylene oxide copolymer and a macromer thereof or polyvinylpyrrolidone as a template. More specifically, the above components and the like may be prepared by thermal polymerization or photopolymerization. It is to prepare a new mucoadhesive polymer composite bonded by the hydrogen bond between the mold and polyacrylic acid by molding the acrylic acid, it can be used in the mucoadhesive drug delivery system using the mucoadhesive property of the obtained composite.