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COMPOUNDS EXHIBITING SELECTIVITY WITH RESPECT TO RETINOID RECEPTORS, PHARMACEUTICAL COMPOSITION (VARIANTS), METHOD OF MODULATION OF PROCESSES (VARIANTS), METHOD OF SUPPRESSION OF PATHOLOGICAL STATES
COMPOUNDS EXHIBITING SELECTIVITY WITH RESPECT TO RETINOID RECEPTORS, PHARMACEUTICAL COMPOSITION (VARIANTS), METHOD OF MODULATION OF PROCESSES (VARIANTS), METHOD OF SUPPRESSION OF PATHOLOGICAL STATES
FIELD: organic chemistry, medicine, pharmacy. SUBSTANCE: invention describes the novel compounds of the general formula (I) where values R1-R5,R14, Q, n are given in p. 1 of the invention claim. Compounds show the selective activity with respect to specific receptors of retinoic acid. They can be used for treatment of patients with different pathological states. Invention describes also pharmaceutical composition based on compounds of the formula (I) and the method of SUPPRESSION of pathological states and the method of modulation of processes (variants). EFFECT: valuable properties of new compounds. 26 cl, 12 dwg, 51 ex
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机译:领域:有机化学,医学,药学。物质:本发明描述了通式(I)的新型化合物<图像文件=“ 00000002.GIF” he =“ 37” imgContent =“ undefined” imgFormat =“ GIF” wi =“ 30” />其中值R 1 Sub> -R 5 Sub>,R 14 Sub>,Q,n在p中给出。本发明的权利要求1。化合物对视黄酸的特定受体表现出选择性活性。它们可用于治疗具有不同病理状态的患者。本发明还描述了基于式(I)化合物的药物组合物,病理状态的抑制方法以及过程(变体)的调节方法。效果:新化合物的宝贵特性。 26 cl,12 dwg,51 ex
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