, inosine of the formula (II) , xanthosine of the formula (III) , deoxyinosine of the formula (IV) , deoxyguanosine of the formula (V) , inosine-2', 3'-(acyclic)-dialcohol of the formula (VI) or their pharmaceutically acceptable salts. Values of radicals RA,RB,RC,RD, Y, Q and Z are given in corresponding points of the invention claim. Invention describes a pharmaceutical composition stimulating hemopoiesis and containing derivatives of guanosine or inosine or their salts as an active agent. Invention proposes also method of treatment of animals with cytopenia by administration of indicated compounds in effective doses. Invention can be used in medicinal practice and therapy in hemopoiesis disorders. EFFECT: compounds indicated above, valuable medicinal properties. 17 cl, 68 dwg, 53 ex"/>
ACYL DERIVATIVES OF GUANOSINE, INOSINE, XANTHOSINE, DEOXY-INOSINE, DEOXYGUANOSINE, INOSINE-2',3'-(ACYCLIC)-DIALCOHOL OR THEIR PHARMACEUTICALLY ACCEPTABLE SALTS, HEMOPOIESIS-STIMULATING PHARMACEUTICAL COMPOSITION, METHOD OF TREATMENT OF CYTOPENIA
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ACYL DERIVATIVES OF GUANOSINE, INOSINE, XANTHOSINE, DEOXY-INOSINE, DEOXYGUANOSINE, INOSINE-2',3'-(ACYCLIC)-DIALCOHOL OR THEIR PHARMACEUTICALLY ACCEPTABLE SALTS, HEMOPOIESIS-STIMULATING PHARMACEUTICAL COMPOSITION, METHOD OF TREATMENT OF CYTOPENIA
ACYL DERIVATIVES OF GUANOSINE, INOSINE, XANTHOSINE, DEOXY-INOSINE, DEOXYGUANOSINE, INOSINE-2',3'-(ACYCLIC)-DIALCOHOL OR THEIR PHARMACEUTICALLY ACCEPTABLE SALTS, HEMOPOIESIS-STIMULATING PHARMACEUTICAL COMPOSITION, METHOD OF TREATMENT OF CYTOPENIA
FIELD: organic chemistry, heterocyclic compounds, pharmacy. SUBSTANCE: invention relates to the novel acyl derivatives of guanosine of the formula (I) , inosine of the formula (II) , xanthosine of the formula (III) , deoxyinosine of the formula (IV) , deoxyguanosine of the formula (V) , inosine-2', 3'-(acyclic)-dialcohol of the formula (VI) or their pharmaceutically acceptable salts. Values of radicals RA,RB,RC,RD, Y, Q and Z are given in corresponding points of the invention claim. Invention describes a pharmaceutical composition stimulating hemopoiesis and containing derivatives of guanosine or inosine or their salts as an active agent. Invention proposes also method of treatment of animals with cytopenia by administration of indicated compounds in effective doses. Invention can be used in medicinal practice and therapy in hemopoiesis disorders. EFFECT: compounds indicated above, valuable medicinal properties. 17 cl, 68 dwg, 53 ex
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机译：领域：有机化学，杂环化合物，药学。物质：本发明涉及式（I）的鸟苷的新型酰基衍生物。<图像文件=“ 00000008.GIF” he =“ 39” imgContent =“ undefined” imgFormat =“ GIF” wi =“ 43” />，肌苷公式（II）的，公式（III）的黄嘌呤，式（IV）的脱氧肌苷<图像文件=” 00000011.GIF“ he =” 39“ imgContent = “ undefined” imgFormat =“ GIF” wi =“ 43” />，公式（V）的脱氧鸟苷<图像文件=“ 00000012.GIF” he =“ 39” imgContent =“ undefined” imgFormat =“ GIF” wi =“分子式（VI）的45“ />，肌苷2'，3'-（无环）-二元醇或其药学上可接受的盐。给出了基团R A ，R B ，R C ，R D ，Y，Q和Z的值在本发明权利要求的相应点中。本发明描述了一种刺激造血的药物组合物，其包含鸟苷或肌苷的衍生物或其盐作为活性剂。本发明还提出了通过以有效剂量施用所示化合物来治疗患有血细胞减少症的动物的方法。本发明可用于造血障碍的医学实践和治疗。功效：上述化合物，有价值的药用特性。 17 cl，68 dwg，53 ex
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