New N-acylated ergoline amine derivatives, are alpha-1 adrenoreceptor blockers useful as potent, well tolerated antihypertensive agents

摘要

N-Acylated aminomethyl-ergoline derivatives (I) are new. N-Acylated aminomethyl-ergoline derivatives of formula (I) and their salts are new. R5 = H, alkyl, aryl, acyl or CN; R6 = H, alkyl or halo; R7, R8 = H or together form a bond; R1 = residue of a diamine; R4 = residue of a dicarboxylic acid; R2 = H or acyl; R3 = H; or R2, R3 = residue of a diamine.