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Divisible solid dosage forms and processes for their manufacture

机译:可分开的固体剂型及其制造方法

摘要

The invention relates to solid, oblong dosage forms (10) comprising a longitudinal axis (11) and a length (L) defined by the projection of the ends (12, 13) of the dosage form on the longitudinal axis. A cross-sectional area (14, 15, 16) oriented in a vertical manner in relation to the longitudinal axis (11) comprises a surface measure which varies along said longitudinal axis (11). The surface measure increases toward both ends (12, 13) in an essentially continuous manner from a cross-sectional area (15), said cross-sectional area being located between the ends (12, 13) and having a minimal surface measure, up to a respective cross-sectional area (14 or 16) having a maximum surface measure. The inventive dosage forms are characterized in that the distance of the maximum cross-sectional area (14), said cross-sectional area (14) being located in the vicinity of one end (12), from the maximum cross-sectional area (16), said cross-sectional area (16) being located in the vicinity of the other end (13), is greater than half the length (L) of the dosage form (10) in a projection on the longitudinal axis (11).
机译:本发明涉及固体的椭圆形剂型(10),其包括纵轴(11)和由剂型的末端(12、13)在纵轴上的投影所限定的长度(L)。相对于纵向轴线(11)以垂直方式定向的横截面(14、15、16)包括沿着所述纵向轴线(11)变化的表面尺寸。所述表面尺寸从横截面(15)以基本上连续的方式朝向两端(12、13)增加,所述横截面位于端部(12、13)之间,并且具有最小的表面尺寸。具有最大表面尺寸的相应横截面区域(14或16)。本发明剂型的特征在于,最大横截面面积(14)与最大横截面面积(16)之间的距离(所述横截面面积(14)位于一端(12)附近)。所述横截面积(16)位于另一端(13)的附近,大于在纵向轴(11)上的投影中剂型(10)的长度(L)的一半。

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