Glial cell activating factor and its production

摘要

Disclosed are (1) a novel glia activating factor which has glial cell growth promoting activity; (2) a glia activating factor containing a polypeptide represented by the following amino acid sequence: IMAGE (3) a DNA containing a following polynucleotide coding for a glia activating factor: IMAGE (4) a host transformed with a vector containing the DNA described in (3); and (5) a method for producing the above glia activating factor which comprises cultivating the transformant described in (4) in a medium, accumulating the glia activating factor in a culture broth, and collecting the resulting glia activating factor.