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INNOVATIVE ENDOTHELCELL MOLECULE THAT MEDIATES THE BINDING OF LYMPHOCYTES IN HUMANS
INNOVATIVE ENDOTHELCELL MOLECULE THAT MEDIATES THE BINDING OF LYMPHOCYTES IN HUMANS
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机译:介导人类淋巴细胞结合的创新内皮细胞分子
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摘要
A novel endothelial cell molecule, VAP-1, that mediates lymphocyte binding in man, is described. Anti-VAP-1 monoclonal antibodies are described and the monoclonal antibody 1B2 is provided by this invention, as well as the hybridoma cell line (DSM ACC2041) which produces it. This invention further provides methods for the treatment of inflammatory and autoimmune diseases by the administration of VAP-1 binding compounds, such as anti-VAP-1 antibodies.
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