insatures derivatives in position 4 of 6 - tert - butyl - 1 and their use in medicine, dimethylindane human or veterinary as well as in cosmetics

摘要

Unsaturated derivatives in position - 4 of 6 -, - - - (1,1 dimethylindan of formula: (see appended drawing in bopi) x represents: (i) is a radical of formula: (a) (see appended drawing in bopi) and y represents a radical of formula: (b) (see appended drawing in bopi) (ii) is a radical of formula: (c) (see appended drawing in bopi) and y represents a radical of formula (b) is a radical of formula: (see appended drawing in bopi) z being - o -, - s - or (see appended drawing in bopi) n - r3, r1 represents - ch3, - (ch2), p - cor4, - (ch2), p - cor5, or - s (o) t - r6, p is 0, 1, 2 or 3, t being 0, 1 or 2, r2 represents h or lower alkyl, r3 represents h, lower alkyl or - cor7, r4 represents h, lower alkyl, - cor7, aryl, aralkyl, mono- or polyhydroxyalkyl, or a polyether radical, r5 represents h, lower alkyl, - or8, or - n (r ′) (r), r7, is a lower alkyl, r8 represents h, alkyl, alkenyl, alkynyl, aryl, aralkyl, mono - or polyhydroxyalkyl, a sugar residue or acid aminé.r 'and r ″ represent h, lower alkyl, - cor7, aryl, a sugar residue, or of amino acid or r' and r "form a heterocycle and the salts of the compounds of formula (i). Use in the topical and systemic treatment of dermatological conditions as in cosmetics.