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Human mutant tissue factor compositions useful as tissue factor antagonists
Human mutant tissue factor compositions useful as tissue factor antagonists
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机译:用作组织因子拮抗剂的人突变组织因子组合物
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摘要
The present invention describes a mutant human tissue factor protein which binds functional Factor VII/VIIa but is substantially free of functional procoagulant cofactor activity, and compositions containing the mutant protein. Also disclosed are methods for using the mutant human tissue factor proteins, and recombinant DNA vectors for expressing the protein.
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