Synthetic polypeptides corresponding to portions of proteinoids translated from brain-specific mRNAs, receptors, methods and diagnostics using the same

摘要

Antibodies or epitope-binding portions thereof raised to a synthetic polypeptide having an amino acid sequence that corresponds substantially to an amino acid residue sequence of at least a portion of a naturally occurring proteinoid and having a molecular weight equal to less than that of the proteinoid are diclosed. That proteinoid contains an amino acid residue sequence translated from a messenger RNA present substantially only in brain cells. Those antibodies or epitope- containing portions bind specifically when admixed with brain cell tissue that includes the naturally occurring proteinoid.