Manufacturing method null of S hydroxypropyl L

摘要

PURPOSE: To profitably obtain the subject cysteine compound by reacting cysteine hydrochloride with allylalcohol in the presence of a radical initiator. ;CONSTITUTION: (A) Cysteine or cysteine hydrochloride is reacted with (B) allylalcohol in the presence of (C) a radical initiator (e.g. sodium persulfate) and (D) a reducing agent (e.g. ferrous chloride) under the irradiation of light (e.g. light having a wave length of 250-260nm for approximately 10-60min) to obtain the objective cysteine compound. The component A and the component B are used in a molar ratio of approximately 1:1.5-2.5, and the component C and the component D are used in amounts of 10wt.% and 5-10wt.%, respectively. The solvent is e.g. water or alcohol. The reaction is preferably performed at 0°C to room temperature for 5-60min. Further, 2,2-dimethylthiazolidine-4- carboxylic acid is preferably reacted with a 3-halogen-1-propanol at a pH of 8-10, and the obtained reaction mixture is reacted with a reducing agent (e.g. sodium sulfide).;COPYRIGHT: (C)1996,JPO