METHOD FOR ASSESSING TOXICITY OF AND METHOD FOR IDENTIFYING CHEMICAL SUBSTANCE

摘要

PROBLEM TO BE SOLVED: To provide the subject two methods having resolved such a problem that, conventional bioassays rely on cell growth inhibition or specific biological reaction as index, resulting in limited amount of information to be obtained; in such a bioassay system, although the presence/absence of toxicity due to chemical substance(s) in the environment can be assessed, neither information concerning such toxicity's characteristics nor information for judging what kind of chemical substance(s) has(have) caused the toxicity is available. ;SOLUTION: The two methods, i.e., a method for assessing the toxicity of and a method for identifying chemical substance(s) in question, comprise culturing cells in the presence of chemical substance(s) to be assessed and simultaneously observing the expressed state for the genes in the above cells.;COPYRIGHT: (C)2001,JPO