CHIRAL LEAD CATALYST AND ASYMMETRIC ALDOL REACTION METHOD

摘要

PROBLEM TO BE SOLVED: To provide a new asymmetric synthesis catalyst with a high yield and high optical selectivity, capable of being used for a simple and general purpose reaction operation, and an asymmetric synthesis method using this catalyst.;SOLUTION: A chiral lead catalyst containing a lead compound represented by formula Pb(ORf)2 (wherein Rf is a fluorine-containing alkylsulfonyl) and a chiral crown ether compound having a skeleton represented by formula 1 is provided, and an asymmetric aldol reaction using this catalyst is carried out.;COPYRIGHT: (C)2001,JPO