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Production method of the amino peptidase and the natural protein which are derived from the bashirasurikenihuomisu strain
Production method of the amino peptidase and the natural protein which are derived from the bashirasurikenihuomisu strain
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机译:巴拉苏里肯尼霍米苏菌株衍生的氨基肽酶和天然蛋白的生产方法
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摘要
The present invention relates to a process for removing methionine (Met) residue at N-terminus of proteins specifically. Particularly, the present invention relates to an aminopeptidase which is purified from Bacillus licheniformis removes a methionine residue from N-terminus of peptide and proteins. And the present invention relates to a process for preparing a natural type protein from proteins produced in microorganisms by recombinant DNA technology. Various kinds of natural type proteins such as human growth hormone (HGH) can be prepared massively and easily by the process of the present invention.
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