METHOD FOR MANUFACTURING REACTIVE CHIP, REACTIVE CHIP MANUFACTURED BY THE METHOD AND REACTIVE SUBSTANCE

摘要

PROBLEM TO BE SOLVED: To provide a method in which a reactive chip is manufactured in such a way that a reactive substance such as a DNA fragment or the like which can be prepared economically is integrated with a high integration degree by a method wherein a photolithographic installation is not required when a probe is synthesized or when the probe is mounted on a substrate, a sample such as the high-cost and valuable DNA fragment or the like capable of being obtained only in an extremely limited amount is used as the probe and the sample is used quickly, surely and in an extreme trace amount, to provided a reactive chip which is manufactured by the method, to provide a method in which a reactive substance such as a DNA fragment or the like is synthesized quickly and economically and to provide a reactive substance which is manufactured by the method. ;SOLUTION: A reactive substance such as a DNA fragment or the like in a prescribed amount is mounted, at high speed and by using a jet nozzle, on a prescribed spot on a substrate on which spots in the prescribed number are formed. Thereby, a reactive chip in which the reactive substance is integrated on its surface with a high integration degree is manufactured. By using a method for its manufacture, reactive substances such as peptides or the like in a small amount but in kinds exceeding several thousands are synthesized at a time, quickly and economically.;COPYRIGHT: (C)2001,JPO