首页> 外国专利> A composition comprising urea derivatives or carbonate and neurotrophic factors to stimulate the growth of neurites in nerve cells and that includes a

A composition comprising urea derivatives or carbonate and neurotrophic factors to stimulate the growth of neurites in nerve cells and that includes a

机译:包含尿素衍生物或碳酸盐和神经营养因子以刺激神经细胞中神经突生长的组合物,其包括

摘要

Methods and Pharmaceutical compositions for Stimulating neurite growth in nerve cells.The compositions comprise a cantidadneurotrofica of a compound of formula (i) and a neurotrophic factor, such as Nerve Growth Factor (NGF).The Methods involve treating nerve cells with the above compositions or compositions comprising the compound without a neurotrophic factor.The Methods of the present invencionpueden Service be used to promote neuronal damage caused by disease or physical trauma.In the formula (i), the substituents a, B, D, I, K, Z, R1 and R2 have the meanings given in the description.
机译:刺激神经细胞中神经突生长的方法和药物组合物。该组合物包含式(i)化合物的念珠菌神经营养因子和神经营养因子,例如神经生长因子(NGF)。本发明的方法用于促进由疾病或身体创伤引起的神经元损伤。在式(i)中,取代基a,B,D,I,K,Z, R1和R2具有说明书中给出的含义。

著录项

  • 公开/公告号AR015105A1

    专利类型

  • 公开/公告日2001-04-18

    原文格式PDF

  • 申请/专利权人 VERTEX PHARMACEUTICALS INCORPORATED;

    申请/专利号AR1997P105320

  • 发明设计人

    申请日1997-11-13

  • 分类号A61K31/44;A61K31/445;A61K31/535;A61K31/47;A61K38/18;A61K45/06;A61P25/00;

  • 国家 AR

  • 入库时间 2022-08-22 01:26:22

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