An amino derivative that has neural activity, a composition containing same and Uses Thereof For Stimulating neural activity

摘要

This is related to the drug compounds, methods and components that stimulate the nerve growth of nerve cells. The compounds, components and methods can be used alone or in combination with nerve factors, such as nerve decline factors, To promote the repair of nerve injury caused by disease or physical trauma A derivative characterized by formula (I) and a pharmaceutically acceptable derivative of formula, wherein a and B are independently selected from hydrogen, AR, rectal 1-6 matrix or branch,straight or branched C2-6 alkenyl or alkynyl, straight chain or branched C1-6 alkyl substituted conc5-C5-7 alkyl, straight or branched C2-6 alkynyl or substituted with C5-7 cyclo-alkyl, alkyl C1-6 straight or branched chain substituted with C5-7 cyclo-alkenyl, C2-6 straight or branched alkenyl or alkynyl substituted with C5-7 cyclo-alkenyl, branched straight chain C1-6 alkyl substituted with Ar, alkenyl or alkynyl C2-6 straight or branched chain substituted with Ar, wherein any of the CH2 groups of said alkynyl, alkenyl or alkyl chains in A or B is optionally replaced by O, S, S (O),S (O) 2 o N (R)R is selected from hydrogen, C1-6 straight chain or loose tar, alquenilo or c2-6 straight chain or loose oil reservoir; R is selected from phenyl, 1-naftil, 2-naftillo, indenil, azlenilo, fluorescence, antracenilo, 2-furil, 3-flier, 2-tienilo, 2-piridilo, 3-piridio, 4-pirilio, pirroo, azolilo, Lilo, 1,1,2,2,3,3,1,1,1,1,1,2,1,2,3,1,1,2,1,1,1,1,1,3,1,2,4-thiodiazepine, benzoxazolilo, pyridine, pyridinePyridine, 1,3,5-cyanogen, 1,3,5-cyanogen, indolizini, indolilo, isoindolilo, 3H indolilo, indolilo,