首页> 外国专利> A Liquid formulation,Non aqueous polymeric material to form in situ a pharmaceutically acceptable and use for preparing a drug for the treatment of disorders of the Upper Gastrointestinal Tract.

A Liquid formulation,Non aqueous polymeric material to form in situ a pharmaceutically acceptable and use for preparing a drug for the treatment of disorders of the Upper Gastrointestinal Tract.

机译:一种液体制剂,非水性聚合物材料,其原位形成药学上可接受的,并用于制备治疗上消化道疾病的药物。

摘要

A polymeric material acceptable from the standpoint of pharmacist in situ in a Body Surface in which the material is formed by lareaccion of (i) an Anionic Polymer or tripolifosfat(Component a) and or (ii) a cationic Polymer (Component b) in the presence of water.Process for the preparation of pharmaceutically acceptable Polymer Material comprises applying (i) an Anionic Polymer or tripolyphosphate (Component a), and (ii) unpolu00edmero cationic (Component b)Orporal tosurface C, in which the component) can REACT with the component (b). Preferably the polymeric film is a cover, or a bioadhesive gel.The Polymers are applied preferably sequentially and the primerpolu00edmero Applied and Sun bioadhesive Polymer.Preferably the component) has one or more acid groups, for example: - COOH and / or - SO3H. Preferably, the componenteb) has one or more Core groups, for example - NH2 and / or nhch3.Other Objects of the invention are US or components and the composition of the material and to lapreparacion Pharmaceutical Packaging for these components.
机译:从药剂师原位在身体表面的观点出发可接受的聚合材料,其中该材料是通过在(a)中释放(i)阴离子聚合物或三叶磷(组分a)和/或(ii)阳离子聚合物(组分b)形成的。药学上可接受的聚合物材料的制备方法包括将(i)阴离子聚合物或三聚磷酸盐(组分a)和(ii)非极性聚阳离子(组分b)孔C涂在表面C上,其中该组分可以与组分(b)反应。优选地,聚合物膜是覆盖物或生物粘附性凝胶。优选地顺序施用聚合物,并且底漆和/或Sun生物粘附性聚合物施用底漆。优选地,组分)具有一个或多个酸基,例如:-COOH和/或-SO3H。优选地,组分eb)具有一个或多个核心基团,例如-NH 2和/或nhch 3。本发明的其他目的是US或组分和材料的组成,并且用于这些组分的药物包装。

著录项

  • 公开/公告号AR016850A1

    专利类型

  • 公开/公告日2001-08-01

    原文格式PDF

  • 申请/专利权人 RECKITT BENCKISER HEALTHCARE (UK) LIMITED;

    申请/专利号AR1998P104145

  • 发明设计人

    申请日1998-08-21

  • 分类号A61L15/22;A61K9/00;A61L15/44;A61L26/00;

  • 国家 AR

  • 入库时间 2022-08-22 01:26:16

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