Generic protein, nucleic acid alone, recombinant cell, processes to produce a chimeric protein, and to obtain a chimeric protein, product, and, test to triate an amino acid sequence as to the ability to improve the folding of an insulin precursor

摘要

QUIRIC PROTECTION, NUCLEICO ISOLATED CIRCLE, RECOMMENDING CELL, PROCEDURES TO PRODUCE A QUIRIC PROTECTION, AND TO OBTAIN A MEDICAL PROTECTION, PRODUCT, AND, TEST TO TRIAL AN AMINE QUALITY OF CAPACITY FOR IMPROVING THE DOBRATION OF AN INSULIN PRECURSOR"This invention refers to the chimeric protein containing a sequence similar to the intramolecular companion (BMI) linked to the target protein, preferably a precursor of insulin. This invention also refers to a process to obtain a chimeric protein containing insulin-precursor currently bent, including, among other things,contact an incorrectly folded chimeric protein containing a similar IMC-sequence linked to an insulin precursor with at least one Optopian auxiliary agent. The present invention also refers to a test to triage an amino-acid sequence as to the ability to improve folding of the insulin precursor by employing a chimeric protein containing a similar-IMC sequence linked to an insulin precursor.