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Proteasome 20s beta-ketoamide inhibitors

机译：蛋白酶体20sβ-酮酰胺抑制剂

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摘要

B 244 -KETOAMIDE PROTEASOME 20S INHIBITORS D 244 -Ketoamide compounds useful for the treatment of 20S proteasome-mediated disorders in mammals, having the following structure (I).

机译： <244>-酮酰胺化的20S抑制剂 <244>-酮酰胺化合物，用于治疗哺乳动物的20S蛋白酶体介导的疾病，具有以下结构（I）。 展开▼

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公开/公告号BR9907256A

专利类型

公开/公告日2001-10-09

原文格式PDF

申请/专利权人 CV THERAPEUTICS INC.;
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申请/专利号BR19999907256

发明设计人 LISA WANG;ROBERT T. LUM;STEVEN R. SCHOW;ALISON JOLY;SURESH KERWAR;MICHAEL M. WICK;
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申请日1999-01-19

分类号C07K5/03;C07K5/027;C07K5/023;C07K5/062;C07K5/083;A61K38/04;

国家 BR

入库时间 2022-08-22 01:26:00

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1. 20S蛋白酶体α－酮酰胺抑制剂 [P] . 中国专利： CN1289340A . 2001-03-28

2. 酮酰胺免疫蛋白酶体抑制剂 [P] . 中国专利： CN104837858A . 2015-08-12

3. Procedure for Isolation of 20S proteasome, and procedure for identifying proteasome inhibitors 20s and 26s. [P] . ES2275044T3 . 2007-06-01

机译：分离20S蛋白酶体的程序，以及鉴定20s和26s蛋白酶体抑制剂的程序。

4. procedures for the isolation of the 20s proteasome, and methods for identification of inhibitors of the 20s and 26s proteasome [P] . 德国专利： DE50305399D1 . 2006-11-30

机译： 20s蛋白酶体的分离步骤，以及20s和26s蛋白酶体抑制剂的鉴定方法

5. procedures for the isolation of the 20s proteasome, and methods for identification of inhibitors of the 20s and 26s proteasome [P] . AT343002T . 2006-11-15

机译： 20s蛋白酶体的分离步骤，以及20s和26s蛋白酶体抑制剂的鉴定方法

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