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Procedure for the preparation of 2-oxazolines imidazolines and derivatives and 2 - in the absence of Solvents under Microwave irradiation
Procedure for the preparation of 2-oxazolines imidazolines and derivatives and 2 - in the absence of Solvents under Microwave irradiation
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机译:微波辐射下在无溶剂的情况下制备2-恶唑啉咪唑啉及其衍生物和2-的步骤
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摘要
The Invention relates to the fields of Organic Chemistry and the use of Heterocyclic irradiation by Microwave as energy source and in the absence of Solvents for the synthesis of 2 - oxaZolinas and 2 - imidazolines and Derived by a method of Successive reactions or by Direct Synthesis Condensation - ciclodeshidrataciu00f3n tandemResults of the interactions between the carboxylic acids or Fatty methyl esters, Ethyl and between 22 and 46 carbon Atoms in front to b-aminoalcohols or 1,2 diamines.Obtaining the carboxamidas intermediary, Isolation,Characterization and subsequent cyclization to the corresponding Heterocycles are exemplified by pre Irradiation of departure allowing togetherThe effect of Microwave, significant improvements in Chemical reactivity and selectivity in comparison with Classical Methods Of Synthesis.Synthesis of a wide variety of Molecules of known Biological activity as well as marketable in the fields of Chemical Industry, Textile Materials, additives, fuelAmong others are exemplified.
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