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Procedure for the preparation of 2-oxazolines imidazolines and derivatives and 2 - in the absence of Solvents under Microwave irradiation

机译:微波辐射下在无溶剂的情况下制备2-恶唑啉咪唑啉及其衍生物和2-的步骤

摘要

The Invention relates to the fields of Organic Chemistry and the use of Heterocyclic irradiation by Microwave as energy source and in the absence of Solvents for the synthesis of 2 - oxaZolinas and 2 - imidazolines and Derived by a method of Successive reactions or by Direct Synthesis Condensation - ciclodeshidrataciu00f3n tandemResults of the interactions between the carboxylic acids or Fatty methyl esters, Ethyl and between 22 and 46 carbon Atoms in front to b-aminoalcohols or 1,2 diamines.Obtaining the carboxamidas intermediary, Isolation,Characterization and subsequent cyclization to the corresponding Heterocycles are exemplified by pre Irradiation of departure allowing togetherThe effect of Microwave, significant improvements in Chemical reactivity and selectivity in comparison with Classical Methods Of Synthesis.Synthesis of a wide variety of Molecules of known Biological activity as well as marketable in the fields of Chemical Industry, Textile Materials, additives, fuelAmong others are exemplified.
机译:本发明涉及有机化学领域,以及在不存在用于合成2-氧杂唑啉和2-咪唑啉的溶剂的情况下通过微波作为能量源并通过连续反应或直接合成缩合得到的杂环辐射的用途。羧酸或脂肪甲酯,乙基与b-氨基醇或1,2二胺前面的22至46个碳原子之间的相互作用的结果。获得羧甲酰胺类中间体,分离,表征和随后的环化反应相应的杂环化合物可以通过预辐照离去进行示例,从而可以使微波共同作用,与经典的合成方法相比,可以显着提高化学反应性和选择性。合成多种已知生物学活性的分子,并且可以在化学领域中销售工业,纺织材料,添加剂,燃料这些是示例。

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