首页> 外国专利> A device for performing an assay using a membrane for the manufacture of the device kit comprising the device and method of detecting an analyte using such a device

A device for performing an assay using a membrane for the manufacture of the device kit comprising the device and method of detecting an analyte using such a device

机译:一种用于使用膜进行测定的装置,用于制造装置套件,该装置包括该装置以及使用该装置检测分析物的方法

摘要

The present invention relates to a device for performing an assay, which device comprises a substrate having oriented through-going channels, said channels opening out on a surface for sample application, the channels in at least one area of the surface for sample application being provided with a first binding substance capable of binding to an analyte. The object of the present invention is to provide a substrate having both a high channel density and a high porosity, allowing high density arrays comprising different first binding substances to be applied to the surface for sample application. More in particular, the object of the present invention is to provide a device comprising a relatively cheap substrate that does not require the use of any typical microfabrication technology and, that offers an improved control over the liquid distribution over the surface of the substrate. The above objects are achieved with a device as mentioned above wherein the porous substrate is an electrochemically manufactured metal oxide membrane.
机译:本发明涉及一种用于执行测定的装置,该装置包括具有定向的贯穿通道的基底,所述通道在表面上敞开以用于样品施加,在所述表面的至少一个区域中提供了用于样品施加的通道。具有能够结合分析物的第一结合物质。本发明的目的是提供一种既具有高通道密度又具有高孔隙率的基底,其允许将包含不同的第一结合物质的高密度阵列施加到用于样品施加的表面上。更特别地,本发明的目的是提供一种包括相对便宜的基板的装置,该基板不需要使用任何典型的微细加工技术,并且提供了对在基板表面上的液体分布的改善的控制。上述目的是通过如上所述的装置实现的,其中多孔基材是电化学制造的金属氧化物膜。

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