IMMUNO-MODULAR EXHIBITING ANTI-MICROBIAL AND ANTI-MYCOBACTERIAL ACTIVITIES, METHOD FOR PRODUCING THE SAME AND PHARMACEUTICAL PREPARATION FOR TREATING MYCOBACTERIOSES ASWELL AS WELL AS CHRONIC AND NON SPECIFIC CONDITIONS, SEXUALLY TRANSMITTED DISEASES AND THE RESULTING IMMUNO-DEFICIENCY

摘要

1. Immunomodulater exhibiting antimicrobial and antimycobacterial activities and representing N-(6-methyl-2,4-dioxo-1,2,3,4-tetrahydro-5-pyrimidinsulfon)-N'-isonicotinoylhydrazide hydrate of the following formula 2. Method for producing an immunomodulater exhibiting antimicrobial and antimycobacterial activities and representing N-(6-methyl-2,4-dioxo-1,2,3,4-tetrahydro-5-pyrimidinsulfon)-N'-isonicotinoylhydrazide hydrate of the following formula characterized by reacting equmolecular amounts of 6-methyluracyl-5-sulfochloride and isoniazide in acetonitrile at an elevated temperature. 3. Pharmaceutical preparation for treating mycobacterioses, pulmonary chronic nonspecific conditions, sexually transmitted diseases and immunodeficiency, comprising an active substance which is an immunomodulator exhibiting antimicrobial and antimycobacterial activities and representing N-(6-methyl-2,4-dioxo-1,2,3,4-tetrahydro-5-pyrimidinsulfon)-N'-isonicotinoylhydrazide hydrate of the following formula and a vehicle. 4. Pharmaceutical preparation according to claim 3, which contains the active substance in an amount of 0.05 to 0.3 g.