Compounds, Pharmaceutical compositions and methods to inhibit Kinases proteinicassolicitante: Agouron Pharmaceuticals, inc.pais: United States of America.

摘要

The present Invention is directed to aminopirazol compounds that mediate and / or inhibit the activity of Protein Kinases, such as Cyclin Dependent Kinases (Cdks),Such as Cdk1, Cdk2, CDK4, Cdk6 and Chk1; VEGF; and Pharmaceutical compositions containing such compounds and compositions.And Methods for treating Cancer and other disease States associated with unwanted angiogenesis and / or cell proliferation.By the provincial Administration of effective amounts of such compounds.