NOVEL SOLID-PHASE SYNTHESIS TECHNIQUES FOR PREPARING MULTIPLE ANALOGOUS COMPOUNDS
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机译:新型固相合成技术,用于制备多种模拟化合物
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摘要
the object of the invention is the procedure more analogue compound are slim way which would, to a solid phase (a), a condensation reagent, intermediate valamilyenlehasu00edtu00f3 / acid.a oldatfu00e1zisu00fakondenzu00e1ciu00f3s product thereby produceda solid phase and a intermediermarad back; (b) the (a) step is separated from the solid phase, the oldatfu00e1zisu00fa kondenzu00e1ciu00f3stermu00e9ket; (c) the residual szilu00e1rdfu00e1zison wore intermeda iert (in step (a), the alkalmazottlehasu00edtu00f3 / condensation reagenstu0151l different splitter / condensation reagensselreagu00e1ltatju00e1k, athe (a) step of condensation product formed during the termu00e9kkeletkezu00e9se oldatfu00e1zisu00fa oldatfu00e1zisu00fakondenzu00e1ciu00f3s analogue; (d) to the step (c) is separated from the resulting product and oldatfu00e1zisu00fakondenzu00e1ciu00f3szilu00e1rd phase; and (e) ku00edvu00e1ntesetben, if residual solid phase, a intermediate vanjelen is repeated once or more, (c) and (d) steps.further, each ismu00e9tlu00e9skor different splitter / condensation reagensalkalmazu00e1su00e1val, additional analogue oldatfu00e1zisu00fa termu00e9kekkeletkezu00e9se during condensation. oh
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