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SYNTHETIC MEMBRANE VESICLES AS VEHICLES CONTAINING FUNCTIONALLY ACTIVE FUSIONAL PEPTIDES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM

机译:包含功能性活性融合肽和组成它们的药物组合物的合成膜囊泡

摘要

the invention relates to a double phospholipid to form cold sores.the membru00e1nhoz functionally connected to at least one of which aktu00edvfu00faziu00f3s peptide and a desired aktu00edvanyagot containing medicine or, uh, therapeutically, and contain a membrane)amelyfoszfatidil ethanol amine and phosphatidylcholine is not virus foszfolipidettartalmaz, vu00edrusfoszfolipiddel together; (b) at least egyfunkcionu00e1lisan active fusion, natural or synthetic, peptidet, where the natural fusion peptide of the hemagglutinintrimer or monomer, one or both of the carcass and the ha1 and ha2glikopeptidek falling within the scope of, and influenzavu00edrusbu00f3l,a positive annakau2013h1n1 altu00edpusu00e1bu00f3l, rabdovu00edrusbu00f3l type iii parainfluenzavu00edrusbu00f3l, semliki forest virus - or togavu00edrusbu00f3l from bifunkcionu00e1liskeresztku00f6tu00e9st training; (c) to obtain,a positive szulfoszukcinimidil - - - - szu00e1rmazu00e9kot amembru00e1n of ethanol aminju00e1hoz tied; and (d) at least egysejtspecifikus marker on the above, membrane - bound keresztku00f6tu00e9st ku00e9pzu0151szerhez tied.the subject of the invention is also gyu00f3gyu00e1szatilagaktu00edv material, in particular szabu00e1lyozottan medicine dispenser, the fentihu00f3lyagocsku00e1kat containing medicinal products.in particular, for the treatment of cancer avu00edrusfertu0151zu00e9sek or medical preparations. a
机译:本发明涉及形成唇疱疹的双磷脂。该膜在功能上连接至至少一种akt,期望的akt,含有药物或在治疗上并含有膜的aktvanyagot。 )阿米福沙地丁乙醇胺和磷脂酰胆碱不是病毒福沙磷酯,而是一起使用; (b)至少是天然的或合成的egyfunkcion活性融合肽,其中血凝素三聚体或单体的天然融合肽,the体和ha1和ha2glikopeptidek中的一者或两者均在以下范围内,并且流感病毒u00f3l,阳性annaka u2013h1n1 alt u00edpus u00e1b u00f3l,rabdov u00edrusb u00f3l iii型副流感病毒 u00edrusb u00f3l,semliki森林病毒-或togavu u00edrusb u00stk t00 k (c)得到正的磺胺嘧啶-咪唑-----乙醇胺,并与之结合; (d)至少在上面的,与膜结合的keresztk u00f6t u00e9st k u00e9pz u0151szerhez系上的埃及标记。本发明的主题也是gy u00f3gy u00e1szati​​lagakt u00edv材料,尤其是分配器,其中含有五种药用产品。特别是用于治疗癌症的药物或药物制剂。一种

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