METHODS OF ALLEVIATING NEUROPATHIC PAIN USING PROSAPOSIN-DERIVED PEPTIDES

摘要

A prosaposin-derived peptide having from about 14-50 amino acids and including the sequence (A), is claimed: Thr-Xaa-Leu-Ile-Asp-Asn-Asn-Ala-Thr-Glu-Glu-Ile-Leu-Tyr (A); Xaa = D-alanine. Also claimed is a method of alleviating or preventing neuropathic pain in a subject, comprising administering an effective amount of an active fragment of prosaposin to the subject.