STABLE GEL FORMULATION FOR TOPICAL TREATMENT OF SKIN CONDITIONS (ACNE, PSORIASIS) COMPRISING ETHYL-6-2-(4,4)- DIMETHYLTHIOCHROMAN-6-YL NICOTINATE IN A PHARMACEUTICAL CARRIER AND A METHOD FOR ITS PREPARATION

摘要

A stable gel formulation for topical treatment of both acne and psoriasis comprising an effective amount of a compound having the formula ethyl-6-[2-(4,4)-dimethylthiochroman-6-yl] nicotinate in a pharmaceutical carrier comprising: (a) water; (b) edetate disodium; (c) ascorbic acid; (d) Carbomer 934P; (e) Poloxamer 407; (f) polyethylene glycol; (g) Polysorbate 40; (h) hexylene glycol; (i) butylated hydroxytoluene; (j) butylated hydroxyanisole; (k) benzyl alcohol; and (l) tromethamine.