Identification of virulence gene cluster from Salmonella typhimurium called virulence gene cluster 2 ( VGC2 )

摘要

A method is described for identifying a molecule which selectively interacts with and substantially inhibits the function of the virulence gene. This in turn reduces the virulence of a microorganism (Salmonella) comprising the step of selecting a compound that interferes with the function of a virulence gene comprising a sequence identified as SEQ ID 8-36, or contained in SEQ ID 37 or 38. Medicaments for treating Salmonella are also described.