Heterotelechelic block copolymer and a polymeric micelle comprising the heterotelechelic block copolymer in an aqueous solvent

摘要

The heterotelechelic block copolymer has the formula (I), wherein: R1 and R2 independently denote C1-10 alkoxy or phenyl-C1-3 alkyloxy, or R1 and R2 combined with each other, denote an ethylenedioxy (-O-CH(R')-CH2-O-: wherein R' denotes H or C1-6 alkyl) which may be substituted with C1-6 alkyl, or, combined with each other, denote oxy (= O). L is a moiety of formula (II) or (III), wherein R3 and R4 independently denote H or C1-10 alkyl, and r denotes an integer of 2-5. m is an integer of 2 - 10 000 n is an integer of 2 - 10 000 p is an integer of 1 - 5 q is an integer of 0 - 20 Z denotes, when q is zero, H, alkali metal, acetyl, acryloyl, methacryloyl, cinnamoyl, p-toluenesulfonyl, 2-mercaptopropionyl or 2-aminopropionyl, or allyl or vinylbenzyl, while, when q is an integer of 1-20, denoting C1-6 alkoxycarbonyl, carboxymercapto or amino.