Androgene activity of steroid (14, 17O) - 17 - (hydroxy)
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机译:类固醇(14,17O)-17-(羟基)的雄激素活性
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摘要
It refers to a kind of sterol compound. Its characteristic is that there are half hydroxyl groups in carbon atom 17, and 14 Di and 17 o components. Carbon 11 in steroids will not be used as a substitute to carry a single or heteromorphic Formula 1, where R1 is O, (h, H),(H OR)NOR; R IS H, C1-C6-ALKYL, C1-C6-ACIL; R2 IS H, C1-C6-ALKYL, HALOGEN; R3 IS H, C1-C6 ALKYL, C2-C6 ALKYNYL, C2-C6 ALKYNYL; R4 IS H, HALOGEN, CYAN, C1-C6 ALKYL, C2-C6 ALKYNYL, C2-C6 ALKYNYL; R5 IS H, C1-C6-ALKYL; R6 IS H, C1-C6 ALCOXY, HALOGEN, C1-C6 ALKYL, AMONG OTHERS; R7 IS H, C1-C6-ALKYL; R8 IS C1-C6 ALKYL; R9 IS H, HALOGEN, CYAN, AMONG OTHERS; R10 IS H, C1-C6 ALCOXY, HALOGEN, CYAN, AMONG OTHERS; OR R10 AND R11 NEXT TO C FORM A CYCLOPROPAN; R11 is H, C1-C6 ALCOXY, HALOGEN, CYAN, C1-C6-ALKYL, C2-C6-ALKYNYL, C2-C6-ALKYNYL; R12 IS H, OH, HALOGEN, CYAN, C1-C6 ALKYL, C2-C6 ALKYNYL, C2-C6 ALKYNYL; R13 AND R14 ARE H, CIANO, FENILO, AMONG OTHERS;R15 is h, SO3H, C1-C6, ACIO c1-c15 The compound is not 20-hydroxy-14, 17o-19-norpregn-4-en-3-ona, (3, 5O, 14, 17O) - pregna-3, 20-diol (3, 14, 17O) - pregna-5, 9 (11) - dien-3, 20-diol (14, 17O) - 20-hydroxi-19-norpregn-4-en-3-ona. Compound I is a steroid hormone; it can be used as a method of male contraception or to treat male malformation.
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