CELLULAR LINES TRANSFECTED BY EXPRESSING AUTOANTIGENES AND THEIR USE IN IMMUNOSENSES FOR AUTO-IMUNE DISEASE DETECTION

摘要

This invention relates to improved in vitro immunoassay methods for detection of autoantibodies associated with autoimmune disease. More specifically, the invention relates to immunoassay methods which utilize a cell line stably transformed with a nucleic acid expressing an autoimmune antigen. This invention also relates to compositions comprising these cell lines and to kits containing such cell lines.